منابع مشابه
Predicting Chemical Toxicity Effects Based on Chemical-Chemical Interactions
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متن کاملAbsence of morphologic correlation between chemical toxicity and chemical carcinogenesis.
The experimental data set used to evaluate site-specific histopathologic correspondence between the morphologic end points of toxicity and carcinogenicity comprises 130 chemical carcinogenesis studies. Nearly 1500 sex-species-exposure-group experiments were evaluated for a) evidence of toxicity or/and carcinogenicity, b) dose-response relationships, c) site-specific correlations of toxicity and...
متن کاملChemical toxicity of red cells.
Exposure to toxic chemicals may result in alterations of red cell function. In certain cases, the toxic effect requires a genetic predisposition and thus affects only a restricted number of individuals; in other instances, the toxic effect is exerted on the hematopoietic system of every person. Glucose-6-phosphate dehydrogenase deficiency is probably the most widespread genetic disorder. It is ...
متن کاملModulation of chemical toxicity and risk assessment.
MUS81 is conserved among plants, animals, and fungi and is known to be involved in mitotic DNA damage repair and meiotic recombination. Here we present a functional characterization of the Arabidopsis thaliana homolog AtMUS81, which has a role in both mitotic and meiotic cells. The AtMUS81 transcript is produced in all tissues, but is elevated greater than 9-fold in the anthers and its levels a...
متن کاملChemical toxicity of the granulocyte.
The effect of chemicals, including pharmacologic agents, on blood granulocytes, may be considered in terms of the effects on the function of mature cells as well as on their number. In turn, the number of cells can be influenced by chemicals which affect production, destruction or distribution within the blood. Neutrophil functions which can be inhibited by chemical agents include chemotaxis, p...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry
سال: 1920
ISSN: 0092-7325,1541-5740
DOI: 10.1021/j150205a003